By the time Jane got home, her aunt _____ for London to attend a meeting. [ ]

A. had left

B. leaves

C. have left

D. left

下列急性化脓性腹膜炎的常见病因，错误的是（）

A.溃疡病急性穿孔

B.急性阑尾炎穿孔

C.肠管损伤破裂

D.直肠下段损伤

E.腹内脏器炎症的扩散