— Whom shall I give the document?

　 — To ________ is in the office. However, _______to require a written paper for it.

A．whom; make sure

B．who; make sure

C．whomever; be sure

D．whoever; be sure

导致发生医疗事故的直接原因是行为主体（）

A.技术上缺乏经验

B.违反医疗卫生管理法律、法规

C.在现有科技条件下无法预料

D.临床诊疗中患者病情异常

E.无法预料或防范